Abstract

Purpose:  To evaluate objective and subjective whitening responses of two marketed vital bleaching systems under intended use conditions.  Materials and Methods:  The randomized clinical trial evaluated 50 adults who received either a combination system with a 3% hydrogen peroxide bleaching gel, pre-formed dual arch tray, dentifrice and oral rinse (Rapid White), or 6% hydrogen peroxide whitening strips (Crest Whitestrips).  Efficacy was assessed objectively from L*a*b* tooth color at Days 7 & 14, while subjective, first-person whitening perception was measured by questionnaire.  A cumulative multinomial probability model was generated to predict subjective responses from objectively measured tooth color.  Results:  At end-of-treatment, adjusted mean b* was –2.05 ± 0.158 for the whitening strip group compared to –0.69 ± 0.141 for the combination group, with these groups differing significantly (P< 0.0001).  This response held across every color parameter and time point in this study.  Relative to the combination system, subjects in the whitening strip group rated that product significantly (P< 0.01) more favorably with respect to the amount of whiteness improvement, as well as whitening satisfaction and overall impression.  These subjective responses were correlated with objective changes in tooth color measured during treatment.  When the b* effect was included in a cumulative multinomial probability model, L*, a*, and treatment were non-significant predictors.  Odds ratios demonstrate that a subject had 3.3 times (1/0.3003 = 3.33) greater odds of selecting a higher whiteness rating when the value of b* was decreased by 1.0 unit (less yellowness).  Similar results were noted for whitening satisfaction and overall impression of treatment.  (Am J Dent 2002;15:7A-12A).

Clinical Significance:  Compared to a combination dentifrice/gel/rinse system, the whitening strips provided superior response at end-of-treatment for both the objective and subjective color parameters tested in the study.