Crest Pro-Health Q&A

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Crest® PRO-HEALTH™ Rinse FAQ's


How does Crest Pro-Health Rinse work?

  • Crest Pro-Health Rinse kills 99% of germs that cause plaque, gingivitis and bad breath, all without the burn of alcohol.
    • Crest Pro-Health contains a clinically proven antibacterial agent, known as CPC, which is attracted to bacteria in your mouth.
    • CPC interacts with the bacterial membrane and solubilizes it, effectively fighting plaque, gingivitis and bad breath for 12 hours.

What is the product made of?

  • The active ingredient in Crest Pro-Health Rinse’s formula is 0.07% Cetylpyridinium chloride (CPC).
    • The active ingredient in Crest Pro-Health Rinse is currently recognized as safe and effective by the FDA monograph. The label meets current FDA monograph standards.
  • The formula’s inactive ingredients may include, but are not limited to, water, glycerin, flavor, poloxamer 407, sodium saccharin, methyl paraben, propyl paraben, propolyne glycol, blue 1, yellow 6, and green 3.


  • The bottle is made of polyethylene terephthalate (PET) and the cap is made of polypropylene.

Are there any other products that use CPC in the market?

  • Yes, however, not all of the products are formulated to provide antiplaque and antigingivitis benefits.
    • Crest Pro-Health Rinse’s innovative formula allows CPC to be available for killing bacteria associated with plaque and gingivitis, as opposed to binding with other inactive ingredients in the formula.
    • The active ingredient in Crest Pro-Health Rinse is currently recognized as safe and effective by the FDA monograph. The label meets current FDA monograph standards.

Does Crest Pro-Health Rinse stain teeth brown?

  • Like all mouthwashes that effectively fight plaque and gingivitis, Crest Pro-Health Rinse can contribute to temporary, surface-level brown tooth discoloration, which is reported by a small percentage of individuals.
    • Tooth discoloration is actually a sign that the product is working: after the rinse kills germs in your mouth, the dead bacteria can collect on the tooth surface and create the appearance of a brown stain.
    • Tooth discoloration could be exaggerated by many other factors, such as existing tartar on teeth, consumption of colored beverages like coffee, tea, red wine, or tobacco use.
    • Brown tooth discoloration from use of mouthwashes that effectively fight plaque and gingivitis is not harmful. It is reversible – and largely preventable – through options like brushing with a power toothbrush and tartar-control/whitening toothpaste, flossing, and visiting your dental professional regularly.

For more information about research assessing stain with antibacterial rinses, click here.


Does Crest Pro-Health Rinse stain teeth blue?

  • Crest Pro-Health Rinse Refreshing Clean Mint flavor contains a blue dye.
    • The dye is safe, will not permanently stain your teeth or tongue, and should wash away with normal eating and drinking.
    • However, you might want to try Crest Pro-Health Rinse Cool Wintergreen flavor, or Crest Pro-Health Night Rinse, neither of which contain blue dye.
  • Some consumers may notice blue specks in their sink after spitting out Crest Pro-Health Rinse Refreshing Clean Mint Flavor.
    • The blue dye in the mouthwash can bind to bacteria in your mouth, making them more visible when you spit into the sink.
    • Some consumers find that running water in the sink before spitting out the rinse helps prevent the blue specks from sticking.

Why doesn't the Crest Pro-Health Rinse label contain a stain warning?

  • The active ingredient in Crest Pro-Health Rinse is currently recognized as safe and effective by the FDA monograph. The label meets current FDA monograph standards.
    • Some other mouthwashes that effectively fight plaque and gingivitis, and have the potential to contribute to temporary brown tooth discoloration, have been on the market for years, and do not carry a stain label.
  • Crest Pro-Health Rinse’s product label does instruct users to “use [the rinse] after your normal brushing and flossing routine.”
    • Brown tooth discoloration from use of mouthwashes that fight plaque and gingivitis is not harmful. It is reversible – and largely preventable – through options like brushing with a power toothbrush and tartar-control/whitening toothpaste, flossing, and visiting the dentist regularly.

What sort of testing has P&G performed on Crest Pro-Health Rinse?

  • We conducted comprehensive studies on Crest Pro-Health Rinse to prove its safety and effectiveness. Information on our clinical and technical data is available on our professional website, www.dentalcare.com.


  • In these studies, the level of temporary, surface-level tooth discoloration found was similar to that of other mouthwashes that effectively fight plaque and gingivitis .

How does Crest Pro-Health Rinse compare to Scope?

  • Scope is a mouthwash that is formulated to kill bad breath germs, providing minty-fresh breath.


  • Crest Pro-Health Rinse provides important health benefits that many ordinary mouthwashes do not.
    • It kills 99% of germs that cause plaque and gingivitis, as well as those that cause bad breath, all without the burn of alcohol

How does Crest Pro-Health Rinse compare to the leading anti-plaque, anti-gingivitis mouthwash?
Both Crest Pro-Health Rinse and the leading anti-plaque, anti-gingivitis mouthwash are formulated to fight germs that cause plaque, gingivitis, and bad breath.

  • But Crest Pro-Health’s unique formula does not contain alcohol.
    • This means that the product does not burn, making it easier to use for the recommended 30 seconds twice daily. If the product is not used for the full 30 seconds, users will not realize the full health benefit.
    • Alcohol – at high concentrations – has been reported to contribute to dry mouth, which can worsen bad breath and the growth of more germs.

Is alcohol needed in mouthwash to kill germs?

  • No.
    • In alcohol-containing mouthwashes, alcohol is not even the active ingredient; it is simply required to stabilize the formula.
    • Alcohol – at high concentrations – has been reported to contribute to dry mouth, which can worsen bad breath and the growth of more germs.
  • Crest Pro-Health Rinse’s alcohol-free formula is a win for millions of consumers who may want to avoid alcohol-based products, but who want to enjoy the health benefits of mouthwash (children or households with children, elderly, diabetics, pregnant women, anyone taking certain prescription medications such as antihypertensives, cholesterol lowering, antidepressants, etc., people with religious considerations, cancer patients, recovering alcoholics, etc.)
    • The no-alcohol formula also means that the product does not burn, making it easier to use for the recommended 30 seconds twice daily. If the product is not used for the full 30 seconds, users will not realize the full benefit.

Does Crest Pro-Health Rinse cause taste loss?

  • Crest Pro-Health Rinse does not cause permanent taste alteration.
    • Oral care products containing active ingredient CPC may cause a temporary aftertaste, or temporary change in the taste of food, in a small percentage of people.
    • CPC stays in the mouth for long periods of time, which allows the rinse to provide its 12-hour benefit.
    • Aftertaste/change in the taste of food typically goes away shortly after product use is stopped.

Why does the Crest Pro-Health Rinse label not contain a taste impairment warning?

  • The active ingredient in Crest Pro-Health Rinse is currently recognized as safe and effective by the FDA monograph. The label meets current FDA monograph standards.


  • The temporary aftertaste, or change in the taste of food, that a small percentage of consumers might experience, typically goes away shortly after product use is stopped.