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Reference: White DJ, Kozak KM, Gibb RD, Dunavent JM, Klukowska M, Sagel PA. J Contemp Dent Pract. 2006; 7(3):1-11
Crest® PRO-HEALTH™ produced a statistically significant reduction in dental plaque coverage 24 hours following last use.
To determine whether the antiplaque efficacy of Crest® PRO-HEALTH™, a dentifrice containinganti-bacterial stannous fluoride (and sodium hexametaphosphate for cosmetic benefits),extended to 24 hours post use.
Morning plaque coverage was 13.3%.
Plaque coverage significantly increased when pre-bedtime brushing was discontinued,with 24-hour growth covering 18.4% of the dentition.
Intervention of the antimicrobial stannous fluoride dentifrice provided significantinhibition of plaque regrowth over 24 hours (15.2% coverage, a 17.4% reduction vs. sodium fluoride dentifrice control).
* Two-sided P-values from a paired-difference t-test.