Reference: Mankodi S, Bartizek RD, Winston JL, et al. J Clin Periodontol. 2005;32(1):75-80.
Over a 6-month period a 0.454% stabilized stannous fluoride (Crest® PRO-HEALTH™) dentifrice showed a statistically significant and clinically relevant effect on the control and prevention of gingivitis compared to a negative control dentifrice (Colgate® Cavity Protection).
To investigate the long-term anti-gingivitis efficacy of a 0.454% stabilized stannous fluoride dentifrice (with sodium hexametaphosphate for cosmetic benefits) compared to a negative control dentifrice.
a Adjusted means and standard errors from analysis of covariance with baseline score as covariate.
b Percent reduction = 100% x (control-experimental mean)/control mean.