Reference: Friesen L, Goyal CR, Qaqish J, et al. J Dent Res 2017; 96 (Spec Iss A): Abstract 0214.
Figure 1. Whole mouth plaque scores at Baseline and Week 4.
N=118. *Statistically significant difference between groups, P<0.0001. **Week 4 values are adjusted means.
Figure 2. Interproximal plaque scores at Baseline and Week 4.
To compare the effect of a SnF2 dentifrice versus triclosan dentifrice on reduction of plaque over a 4-week period.
- Experimental 0.454% stabilized SnF2 dentifrice (Crest® PRO-HEALTH™ Clean Mint [Smooth Formula], Procter & Gamble)
- Triclosan positive control dentifrice with 0.24% sodium fluoride (Colgate® Total®, Colgate-Palmolive). Both groups used a soft, regular manual toothbrush (American Dental Association) and brushed with their respective product according to manufacturer’s instructions at-home.
Chemotherapeutic antimicrobial dentifrices play an important role in the control of plaqueinduced oral diseases, such as gingivitis. Both SnF2 and triclosan dentifrices have been shown to provide significant inhibition of plaque.1,2 This study showed the new smooth formula SnF2 dentifrice provided significantly greater plaque control than the triclosan dentifrice. These findings are consistent with other studies in the literature showing superior plaque protection for SnF2 versus triclosan dentifrice.3,4
1White DJ, et al. J Contemp Dent Pract. 2006;July (7)3:001-011.
2Rover JA, et al. Am J Dent. 2014 Jun;27(3):167-70.
3He T, et al. Am J Dent. 2013;26: 303-306.
4Sharma NC et al. J Clin Dent. 2013;24:31-36.