Reference: Sharma N, He T, Barker ML, Biesbrock AR. J Clin Dent 2013;24:31-36
Both the stannous fluoride dentifrice and the triclosan dentifrice produced a statistically significant reduction from baseline in mean plaque values for whole mouth, gingival margin, and interproximal plaque at Weeks 3 and 6 (P < 0.02 for all comparisons).
The stannous fluoride dentifrice showed a statistically significantly (P < 0.0001) lower adjusted mean plaque level compared to the triclosan group for all three tooth areas at both Weeks 3 and 6. Whole mouth plaque scores for the stannous fluoride dentifrice were 29.7% lower at Week 3 and 44.9% lower at Week 6 than the triclosan dentifrice (Figure 1).
Figure 1. Whole mouth plaque levels at Baseline, Week 3 and Week 6 per group.
- 0.454% stannous fluoride dentifrice (Crest® PRO-HEALTH™ Advanced Deep Clean, Procter & Gamble)
- 0.3% triclosan/0.24% sodium fluoride dentifrice (Colgate Total, Colgate-Palmolive)
Subjects brushed their teeth with a soft manual toothbrush (Oral-B® Indicator™, Procter & Gamble) using their assigned treatment dentifrice according to the manufacturer’s instructions.