Test Preview

  1. Nociception or pain perception is __________.
  1. Which of the following are noxious stimuli that affect “high-threshold” primary afferent sensory neurons or nociceptors?
  1. Which of the following are chemical activators of nociceptors?
  1. Which of the following statements associated with the kinins (bradykinin) is correct?
  1. Which of the following statements is correct with reference to the activation of peripheral sensory neurons?
  1. Which of the following statements is correct with reference to neuronal transmission in the trigeminal nucleus?
  1. Which of the following statement is correct with respect to secondary or tertiary afferent neurons?
  1. Pain arising slowly after injury, which is perceived as burning, aching, dull, poorly localized, and persistent, i.e., second pain, is most likely due to the activation of __________.
  1. Pain arising rapidly after tissue injury, which is perceived as sharp, bright, well-localized, but not particularly persistent, i.e., first pain, is most likely due to the activation of __________.
  1. Which of the following statements is correct with respect to homeostatic mechanisms in excitable neuronal cells?
  1. Which of the following statements is correct with respect to the ionic disequilibrium associated with action potential generation?
  1. Which of the following statements is correct with respect to the mechanism of action of local anesthetic agents (LAs)?
  1. All of the following statements related to the ability of LAs to cross biological membranes are correct EXCEPT which one?
  1. Which of the following statements is correct with respect to the mechanism of action of local anesthetic agents (LAs)?
  1. The rate of absorption of LAs into the systemic circulation is determined by __________.
  1. Which of the following statements is correct relative to the volume of distribution (Vd) of LAs?
  1. All of the following statements are correct with respect to the metabolism of LAs EXCEPT which one.
  1. While the vehicle of LAs is sterile water, formulations may contain __________.
  1. Which of the followings statements related to vasoconstrictors in LAs is correct?
  1. All of the following statements relative to a LA’s potency are correct EXCEPT which one?
  1. All of the following statements relative to a LAs onset of action are correct EXCEPT which one?
  1. All of the following statements relative to a LA’s duration of action are correct EXCEPT which one?
  1. In general, which of the following is the LA of choice, because of its longer duration of action, when the use of a vasoconstrictor is contraindicated?
  1. All of the following statements relative to LAs are correct EXCEPT which one?
  1. Which of the following statements are correct with respect to bupivacaine when compared to other LAs?
  1. A practical approach to determine the dosage of LAs in healthy adults is based on weight, e.g., milligram of drug per pound of body weight; however, if a patient weighs ≥150 lbs. no more than the maximum recommended dose (MRD) should be administered.
  1. Although there are many rules and formulae, manufacturer’s recommendations provide a reasonable approach to calculating pediatric dosages.
  1. All of the following statement related to technical issues, storage, and sterilization/disinfection of LA cartridges are correct EXCEPT which one?
  1. Technical issues related to the administration of LAs that modulate the efficacy of intraoral topical anesthetic agents to reduce needle-insertion pain include __________.
  1. Which of the following statements is correct with respect to phentolamine mesylate for the reversal of soft-tissue anesthesia?
  1. Which of the following statements is correct with respect to local toxicity of LAs?
  1. Which of the following statements is correct with respect to LA-associated CNS toxicity?
  1. Which of the following settlements is correct with respect to LAs’ cardiovascular toxicity?
  1. All of the following statements are correct with respect to LA-induced allergic reactions EXCEPT which one?
  1. Which of the following statements related to methemoglobinemia is correct?
  1. Which of the following statements is correct with respect to the use of vasoconstrictors in conjunction with LAs?
  1. Which of the following statements is correct with respect to the use of LAs during pregnancy?
  1. Which of the following statements is correct with respect to the use of LAs containing a vasoconstrictor during pregnancy?
  1. Which of the following statements is correct with respect to the use of LAs and the nursing woman?
  1. All of the following statements related to LA-related drug-drug interactions are correct EXCEPT which one?