Introduction

A patient’s overall health status determines the patient’s ability to undergo and respond to dental care. Consequently, patient-specific problems that may interfere with the clinical process must be identified. In determining perioperative risk, clinicians must assess the patient’s vital signs and functional capacity; and consider past and present illnesses, major hospitalizations, dietary supplements and special diets, history of drug allergies and other adverse drug reactions (ADRs), and medications taken by the patient.1

In the United States there are approximately 500 Food and Drug Administration (FDA)-approved active ingredients, i.e., therapeutic agents, available in several thousand different formulations.2 ClinCalc DrugStats provides prescription drug utilization data estimates based on the annual Medical Expenditure Panel Survey (MEPS).2 The Top 300 Prescription Drugs represent 60% of all available therapeutic agents and 97% of all prescription drugs dispensed by U.S. community pharmacies.2