Activ Bio-Cleanser™ logo with a stylized hops flower on a dark blue background.

Activ Bio-Cleanser™ Toothpaste Technology

Introducing Crest toothpaste with Activ Bio-Cleanser™, our latest innovation backed by more than ten years of research. Exclusively formulated for Crest toothpastes, this new plant-derived ingredient, extracted from the hops flower, helps disrupt the structural biofilm matrix (EPS) to increase the efficacy of its removal.


The publications below include peer-reviewed research, including studies published in the Compendium of Continuing Education in Dentistry, supporting the science, biofilm-disrupting performance, and in vivo efficacy of Activ Bio-Cleanser™.

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