The patient’s medical history was not significant for any diseases or allergies. There was no history of trauma to the area.
Upon examination, a well-demarcated, dome-shaped, smooth-surfaced, exophytic, pink to focally gray nodule was identified on the ventral surface of the tongue (Figure 1). The lesion was firm to palpation but was not painful, and there was no evidence of calcification associated with the lesion.
Excisional Biopsy Findings
Under general anesthesia, the lesion was completely excised and was found to be a fluid filled cyst-like structure. The fluid was viscous, honey-colored, and was expressed from the central cystic structure. Histologic examination revealed a cyst-like architecture lined by granulation tissue rather than epithelium (Figure 2) and filled with mucoid material, sheets of foamy macrophages, and a few neutrophils (Figure 3). This structure was focally surrounded by skeletal muscle bundles (Figure 2) and minor salivary gland lobules. The latter showed evidence of focal fibrosis and chronic inflammation (Figure 4).