This course presents an overview of dental pit and fissure sealants as a safe and effective way to prevent dental caries. The course starts with a brief look at the history of dental sealants followed by the current rationale for their use. Frequently asked questions about sealants are addressed along with the presentation of guidelines for sealant use. Information about materials currently used for sealants is presented along with general instructions for the successful placement of sealants. The use of sealants in public health programs is also addressed.