Diagnosing RA is challenging even during its early stages due to the variety of symptoms; many appearing similar to other arthritic disorders characterized with intense pain. A rheumatologist, specializing in diseases of connective tissue and joints typically is the one to diagnose and prescribe long-term management approaches. A physical examination, discussion of symptoms, x-rays (Figure 6) and a blood test comprise an essential diagnostic work-up. X-rays may not clearly identify bone changes in early stages; whereas ultrasound and magnetic resonance imaging (MRI) provides greater sensitivity in detecting early joint damage and erosions.51 Immunological testing determines the presence of a specific antibody, rheumatoid factor (RF), identified in approximately 80% suffering with RA after one year.52 Rheumatoid factor-positive patients may also have a higher disease activity score, meaning frequent flare-ups and fewer remission periods.53

Figure 6. X-ray of patient with Rheumatoid Arthritis.
X-ray of patient with Rheumatoid Arthritis

RA is a disabling disease with most daily activities impaired. At least 50% of those diagnosed ten years from onset are unable to maintain full time employment. Those diagnosed before age 45 encounter greater disabilities than those diagnosed at 70+.44

Figure 7. 2010 Rheumatoid Arthritis Classification.54
Chart listing the classification criteria for Rheumatoid Arthritis dwnldpdflo