Confirmation of clinical impression of candidiasis can be obtained by exfoliative cytology. Using a sterile instrument or a tongue blade, the suspected area is scrapped and the harvested material is spread on a glass slide. The application of a few drops of 10% potassium hydroxide (KOH - formulated by your local pharmacist) to the fresh cytological smear will allow for immediate microscopic examination of the preparation (Figure 6). Topical antifungal agents such as nystatin oral lozenges and clotrimazole troches may be prescribed. Systemic fluconazole may be a better alternative.32
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