Ibuprofen, 200 mg, is somewhat more effective than naproxen sodium, 220 mg, and both are more effective than APAP, 650 mg (Table 2).36-40 Consequently, over-the-counter NSAIDs are the drugs of choice for the treatment of mild-to-moderate odontogenic pain. Since APAP has no significant anti-inflammatory activity, in the treatment of odontogenic pain APAP should only be considered as an alternative analgesic, i.e., when NSAIDs are contraindicated.
Table 2. Over-the-counter Analgesics for Mild-to-moderate Odontogenic Pain.
|Drug||Usual oral single dose in milligrams||Dosing||Maximum daily dose in milligrams|
|Ibuprofen (generic, Motrin)||200||q4h||1,200|
|Naproxen sodium |
|Acetaminophen (generic, Tylenol)||650||q4h||3,900|