Preoperative doses of NSAIDs reduce postoperative pain and the need for postoperative opioids analgesics.51,52 It also appears that there may be a window-period, and the timely administration NSAID, i.e., within an hour of a procedure, will provide a similar benefit.53 It has also been reported that when treating irreversible pulpitis, the administration of ibuprofen one hour before administering a local anesthetic agent is an effective strategy for achieving deep anesthesia.54
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