The most common complaint causing a person to seek the services of an oral healthcare provider is pain.1-5 Consequently, the primary obligation and ultimate responsibility of every clinician is to relieve pain. This requires an understanding of the complexity of pain, an appreciation for the factors that determine its expression in the clinical setting, the initiation of disease-modifying procedures (i.e., primary dental care), and the implementation of appropriate perioperative pharmacological strategies. chat Let's get started!