Just as periodontitis is more common in persons with diabetes, poor glycemic control is also associated with peri-implant disease.29 Although the role of distinct phlogistic (inflammatory) mediators in its pathogenesis is not fully elucidated, evidence suggests proinflammatory gene expression at peri-implantitis sites is affected by glycemic control.30 Indeed, the prognosis with dental implants is improved in patients with glycosylated hemoglobin levels below 7 (normal range: 4 to 5.7%).31
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