Healthcare-associated Exposure to Methicillin-resistant Staphylococcus aureus (MRSA)

MRSA is primarily transmitted by direct contact with an infected skin lesion; less frequently by contact with contaminated articles and environmental surfaces.21 PEP is not recommended. Exposed HCP should be monitored for skin lesions, i.e., redness, warmth, swelling, fluctuance, draining pus, fever, and pain at sites that initially may have looked like “spider bites.” Incision and drainage and empirical adjunctive antibacterial coverage are the first step in treating purulent skin infections.21