Primary prevention, i.e., strict adherence to the principles of Standard and Transmission-based precautions is the best means of preventing occupational exposure to blood and OPIM. When an occupational exposure does occur, immediate wound care (when applicable), prompt reporting of the incident, timely postexposure evaluation and initiation of PEP followed by expert follow-up and counseling are the cornerstones to prevent infection and the development of disease.
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