Immunization strategies for oral healthcare personnel (OHCP) are predicated on (1) vaccines mandated or strongly recommended at the time of employment, (2) vaccines recommended for adults in general, and (3) vaccines recommended when other risk factors (other than occupation) are also present. Currently available knowledge related to vaccination strategies in healthcare settings is supported by data derived from well-conducted trials or extensive, controlled observations, or, in the absence of such data, by best-informed, most authoritative opinions available.