If possible, salivary cultures for candidiasis should be performed at baseline in patients with DG in order to determine whether or not candida is present in the oral cavity. If it is present, and if the diagnosis affirms a condition requiring the use of topical or systemic steroids or other immune suppressants, prophylactic antifungal medication may be indicated at the onset of treatment. Culturing is not available in many dental practices so the clinician should consider empirically prescribing an antifungal agent if immunosuppressants are to be used and be especially vigilant for evidence of candidiasis at all follow-up appointments.47
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