Salivary constituents include disease markers such as active peptides, proteins and enzymes; consequently, saliva is an ideal diagnostic fluid alternative to blood.7,8 Salivary biomarkers specific for head and neck carcinoma, oral cancer, breast cancers, gastric cancers, salivary gland dysfunction (e.g., Sjogren’s syndrome), systemic sclerosis, dental and gingival pathology, psychiatric, neurological, and other diseases have been identified.9,10 Saliva sampling is noninvasive and saliva is easier to handle during diagnostic procedures than blood.9
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