Saliva-based Detection of Infectious Diseases

There are more than 1000 nonpathogenic and pathogenic organisms in the oral cavity. For several of the pathogenic organisms such as H. pylori, M. tuberculosis, B. burgdoferi, Shigella, T. solium, and the human immunodeficiency virus (HIV) salivary biomarkers have been identified.52-56 Only OraQuick Advance® Rapid HIV-1/2 Antibody Test (Orasure Diagnostics. Bethlehem, PA), which tests for HIV-specific antibodies, is available for point-of-care use.56