Adverse Drug Reactions - Part I

A History and Update of Fluoride Dentifrices
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This course presents the mechanisms of adverse drug reactions (ADRs), the 30 most common ADRs associated with the top 200 drugs dispensed by U.S. community pharmacies, and less common ADRs that relate to dental therapeutics and/or manifest in the head and neck area. Emphasis is on those ADRs that have a pharmacokinetic or a pharmacodynamic basis and, with the exception of overdose, are the result of drug-drug, drug-food, drug-herbal, and drug-disease interactions with therapeutic doses of drugs.

Please note this is Part I of a two-part series. Adverse Drug Reactions – Part II discusses common immune-mediated and idiosyncratic ADRs related to the top 200 drugs dispensed by U.S. community pharmacies, less commonly noted ADRs affecting oral tissues, and drug-related carcinogenesis and teratogenesis.

Conflict of Interest Disclosure Statement

  • The authors report no conflicts of interest associated with this course.


  • P&G is providing these resource materials to dental professionals. We do not own this content nor are we responsible for any material herein.
  • Participants must always be aware of the hazards of using limited knowledge in integrating new techniques or procedures into their practice. Only sound evidence-based dentistry should be used in patient therapy.

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CE Broker
For all states that use CE Broker for licensure, “proof of completions” are electronically reported the first of every month. If a course was taken in November, the “proof of completion” will be submitted the beginning of December.