Adverse Drug Reactions - Part II

A History and Update of Fluoride Dentifrices
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This course discusses common immune-mediated and idiosyncratic adverse drug reactions (ADRs) related to the top 200 drugs dispensed by U.S. community pharmacies and less commonly noted ADRs affecting oral tissues. In addition, uncommon, time-related (delayed), usually dose-related ADRs, i.e., carcinogenesis and teratogenesis, and some secondary ADRs are presented.

Please note this is Part II of a two-part series. Adverse Drug Reactions – Part I discusses common “on-target,” “off-target,” and (3) cytotoxic reactions related to the top 200 drugs dispensed by U.S. community pharmacies, and less common ADRs that relate to dental therapeutics and/or manifest in the head and neck area.

Conflict of Interest Disclosure Statement

  • The authors report no conflicts of interest associated with this course.


  • P&G is providing these resource materials to dental professionals. We do not own this content nor are we responsible for any material herein.
  • Participants must always be aware of the hazards of using limited knowledge in integrating new techniques or procedures into their practice. Only sound evidence-based dentistry should be used in patient therapy.

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CE Broker
For all states that use CE Broker for licensure, “proof of completions” are electronically reported the first of every month. If a course was taken in November, the “proof of completion” will be submitted the beginning of December.