Prerequisites to considering ADRs in the differential diagnosis of a patient's problem include awareness that there are no “absolutely safe” biologically active agent and familiarity with relevant literature about ADRs. It is equally important to recognize that some ADRs occur rarely and detection based on clinical experience or reports in the literature at times is impossible. The timely reporting of ADRs can save lives, reduce morbidity, and decrease the cost of healthcare. chat Let's get started!