General Principles of Pharmacology

A History and Update of Fluoride Dentifrices
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Introduction - Pharmacology

Pharmacodynamic mechanism, i.e., drug-receptor interactions provide quantitative information that is the basis for determining efficacy, potency, and toxicity of drugs. Pharmacokinetic processes determine the ability of a drug to cross biological membranes, reach its target tissue, and to maintain steady-state concentrations at its site of action. Key points for practice to ensure effective and safe pharmacotherapy, including prescription writing, are presented.

Conflict of Interest Disclosure Statement

  • Dr. Ojeda Diaz reports no conflicts of interest associated with this course.
  • Dr. Terézhalmy has done consulting work for Procter & Gamble and has served on the Advisory Board.


  • P&G is providing these resource materials to dental professionals. We do not own this content nor are we responsible for any material herein.
  • Participants must always be aware of the hazards of using limited knowledge in integrating new techniques or procedures into their practice. Only sound evidence-based dentistry should be used in patient therapy.

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