Cardiovascular Effects

Signs and symptoms of depressed cardiovascular function are the direct effect of LAs on cardiac conduction, excitability, and contractility.2,4-10,19-21,26,27 Early signs of reduced cardiac output include sweating, faintness, and altered mentation; followed by bradycardia, hypotension, and progressive cerebral hypoxia leading to seizures. Depressed cardiac conduction, excitability, and contractility may progress to ventricular arrhythmias, atrioventricular block, and cardiac arrest. chat Let's get started!