Ventilation failure (Table 8) is defined as a rise in CO2 concentration when alveolar ventilation either falls or fails to respond adequately to increased CO2 production. The most common causes are acute exacerbation of asthma and COPD. Asthma is diffuse airway inflammation caused by household (dust mites, pets) and environmental (pollens) allergens in genetically susceptible patients resulting in reversible bronchoconstriction. COPD (chronic bronchitis, emphysema) is a reversible airway obstruction caused an inflammatory response to toxins, e.g., cigarette smoke.
Table 8. Ventilation Failure.
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