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Biological Effects of Radiation

Course Number: 572


Radiotherapy to the head and neck area may significantly affect the developing dentition due to a tooth’s developmental stage and the absorbed dose. A dose of 10 Gy can permanently damage maturing ameloblasts. Ameloblastic activity ceases after exposure to 30 Gy. Radiation-induced defects may include partial or complete anodontia, tooth dwarfism, incomplete root development, premature closure of apices, and localized enamel defects.13