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Biological Effects of Radiation

Course Number: 572

Teeth

Radiotherapy targeting the head and neck can significantly impact the developing dentition, with effects depending on the stage of tooth development and the absorbed radiation dose. Exposure to 10 Gy can permanently damage maturing ameloblasts, while doses of 30 Gy completely halt ameloblastic activity. Radiation-induced abnormalities may include partial or complete anodontia, tooth dwarfism, incomplete root formation, premature apex closure, and localized enamel defects.13