Conclusion

A comprehensive understanding of the host factors influencing caries development is essential for evidence-based decision-making in clinical practice. Recognizing the role of tooth structure, salivary composition, and immune responses—particularly the functions of secretory Immunoglobulin A and Immunoglobulin G—enables dental professionals to implement targeted interventions to reduce subsurface mineral loss and caries risk. Additionally, effectively communicating these factors to patients fosters adherence to preventive strategies, enhancing trust and compliance with at-home oral care recommendations. By integrating this knowledge into clinical practice, dental professionals can optimize patient outcomes and advance caries prevention efforts.