Nicotine Pouches and Oral Health
Course Number: 693
Course Contents
Cancer Risk
Limited data suggests that ONPs are associated with a lower risk of cancer compared to conventional cigarettes. Nicotine itself is not a direct carcinogen.5 Clinical trials found roughly 186 different chemical components were found in the composition of ONPs besides nicotine. At least eight were deemed hazardous. Methyl, eugenol, benzophenone and B-mycrene which are classified as carcinogenic agents to human beings, per to the International Agency for Research on Cancer. Tobacco-specific nitrosamines (TSNAs), which are potent carcinogens were found and presented at lower levels than traditional cigarettes or snus. However, high levels of formaldehyde were persistently detected in ONPs.30 Previously discussed, keratinized tissues could possibly lead to oral squamous cell carcinoma, in reference to mucosal lesions that do not resolve when linked to risk factors such as nicotine and tobacco.24