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Caries Process, Prevention, and Management: Demineralization/Remineralization

Course Number: 714

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References / Additional Resources

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  3. Lemos JA, Palmer SR, Zeng L, Wen ZT, Kajfasz JK, Freires IA, Abranches J, Brady LJ. The Biology of Streptococcus mutans. Microbiol Spectr. 2019 Jan;7(1):10

  4. Nascimento MM. Approaches to Modulate Biofilm Ecology. Dent Clin North Am. 2019 Oct;63(4):581-594.

  5. Cury JA, Ricomini-Filho AP, Tabchoury CPM. Chapter 5.1: Physicochemical Interactions between Enamel and Oral Fluids. Monogr Oral Sci. 2023;31:50-61. doi: 10.1159/000530559. Epub 2023 Jun 26. PMID: 37364552.

  6. Marsh PD. In Sickness and in Health-What Does the Oral Microbiome Mean to Us? An Ecological Perspective. Adv Dent Res. 2018 Feb;29(1):60-65.

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  8. Avery J, Steele PF. Oral Development and Histology. 3rd ed. 2002; New York: Thieme Medical Publishers, Inc; 2002.

  9. Bjørndal L, Ramezanzade S. Chapter 3: Pathological Features of Coronal Caries. Monogr Oral Sci. 2023;31:19-36. doi: 10.1159/000530557. Epub 2023 Jun 26. PMID: 37364550.

  10. Marsh PD, Lewis MAO, Rogers H, et al. Oral Microbiology. 6th ed. 2016; Edinburgh: Churchill Livingstone Elsevier.

  11. Higham SM, Edgar WM. Human dental plaque pH, and the organic acid and free amino acid profiles in plaque fluid, after sucrose rinsing. Arch Oral Biol. 1989;34(5):329-334.

  12. Stookey GK. The effect of saliva on dental caries. J Am Dent Assoc. 2008 May;139 Suppl:11S-17S.

  13. Ahn SJ, Ahn SJ, Browngardt CM, Burne RA. Changes in biochemical and phenotypic properties of Streptococcus mutans during growth with aeration. Appl Environ Microbiol. 2009 Apr;75(8):2517-2527.

  14. Fejerskov O, Nyvad B, Kidd EAM, eds. Dental Caries: The Disease and its Clinical Management. 3rd ed. West Sussex, United Kingdom: Wiley-Blackwell; 2015.

  15. Larsen MJ, Pearce EI, Jensen SJ. Notes on the dissolution of human dental enamel in dilute acid solutions at high solid/solution ratio. Caries Res. 1993;27(2):87-95.

  16. Shellis RP. A scanning electron-microscopic study of solubility variations in human enamel and dentine. Arch Oral Biol. 1996 May;41(5):473-484.

  17. Tanaka M, Margolis HC. Release of mineral ions in dental plaque following acid production. Arch Oral Biol. 1999 Mar;44(3):253-258.

  18. Edgar WM, Dawes C, O’Mullane D. Saliva and Oral Health. 3rd ed. 2004; London, UK: BDJ Books.

  19. Featherstone JD. Dental caries: a dynamic disease process. Aust Dent J. 2008 Sep;53(3):286-291.

  20. Centers for Disease Control and Prevention. Oral Health Surveillance Report: Dental Caries, Tooth Retention, and Edentulism, United States, 2017–March 2020. U.S. Department of Health and Human Services; 2024. Available at: CDC Oral Health Surveillance Rep.

  21. Nascimento MM, Alvarez AJ, Huang X, Hanway S, Perry S, Luce A, Richards VP, Burne RA. Arginine Metabolism in Supragingival Oral Biofilms as a Potential Predictor of Caries Risk. JDR Clin Trans Res. 2019 Jul;4(3):262-270. doi: 10.1177/2380084419834234. Epub 2019 Apr 30. PMID: 31039043; PMCID: PMC6572888.

  22. Nascimento MM, Browngardt C, Xiaohui X, Klepac-Ceraj V, Paster BJ, Burne RA. The effect of arginine on oral biofilm communities. Mol Oral Microbiol. 2014 Feb;29(1):45-54. doi: 10.1111/omi.12044. Epub 2013 Dec 2. PMID: 24289808; PMCID: PMC7003997.

  23. Nascimento MM. Potential Uses of Arginine in Dentistry. Adv Dent Res. 2018 Feb;29(1):98-103. doi: 10.1177/0022034517735294. PMID: 29355411; PMCID: PMC5784480.

  24. Luo BW, Liang NL, Townsend JA, Lo ECM, Chu CH, Duangthip D. Sugar substitutes on caries prevention in permanent teeth among children and adolescents: a systematic review and meta-analysis. J Dent. 2024;146:105069. doi:10.1016/j.jdent.2024.105069

  25. Hara, A. T., & Zero, D. T. (2010). The caries environment: saliva, pellicle, diet, and hard tissue ultrastructure. Dental Clinics of North America, 54(3), 455–467.

  26. Chen D, Chew D, Xiang Q, Lam T, Dai Y, Liu J, Wang L, He T, Strand R, Zhang X, Lim L, Xu J, Shi Y, Dong W. Interactions and effects of a stannous-containing sodium fluoride dentifrice on oral pathogens and the oral microbiome. Front Microbiol. 2024 Feb 15;15:1327913. doi: 10.3389/fmicb.2024.1327913. PMID: 38426054; PMCID: PMC10902866.

  27. Johannsen A, Emilson CG, Johannsen G, Konradsson K, Lingström P, Ramberg P. Effects of stabilized stannous fluoride dentifrice on dental calculus, dental plaque, gingivitis, halitosis and stain: A systematic review. Heliyon. 2019 Dec 9;5(12):e02850. doi: 10.1016/j.heliyon.2019.e02850. PMID: 31872105; PMCID: PMC6909063.

    Additional Resources


    • Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
    • Horowitz AM, Drury TF, Goodman HS, Yellowitz JA. Oral pharyngeal cancer prevention and early detection. Dentists' opinions and practices. J Am Dent Assoc. 2000 Apr;131(4):453-62. doi: 10.14219/jada.archive.2000.0201.
    • Llewellyn CD, Johnson NW, Warnakulasuriya S. Factors associated with delay in presentation among younger patients with oral cancer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jun;97(6):707-13. doi: 10.1016/j.tripleo.2004.01.007.
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    • Rhodus NL. Oral cancer: Early detection and prevention. Inside Dentistry. 2007 Jan;(3)1.
    • Siegel MA, Kahn MA, Palazzolo MJ. Oral cancer: a prosthodontic diagnosis. J Prosthodont. 2009 Jan;18(1):3-10. doi: 10.1111/j.1532-849X.2008.00373.x.
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    • Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A. Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management. J Formos Med Assoc. 2018 Sep;117(9):756-765. doi: 10.1016/j.jfma.2018.01.021. Epub 2018 Feb 19.
    • National Cancer Institute: https://www.cancer.gov/about-cancer/causes-prevention/risk/infectious-agents/hpv-and-cancer.
    • The Cleveland Clinic: Head and Neck Cancer https://my.clevelandclinic.org/health/diseases/14458-head-and-neck-cancer

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