Aging, Systemic Disease and Oral Health: Implications for Women Worldwide (Part II)

Course Number: 330

Oral Connections

Patients suffering with depressive symptoms and undergoing specialized treatments require detailed oral hygiene care. Oftentimes, their depression may have led them to consume non-nutritious diets consisting of highly cariogenic drinks, snacks, and retentive fermentable carbohydrates, all contributing factors for dental caries. Dietary inadequacies have been strongly associated with depressive mood disorders, with growing evidence demonstrating that insufficient intake of key nutrients disrupts neurotransmitter synthesis, immune regulation, and hormonal balance—mechanisms central to mood stability in women across the lifespan. Deficiencies in omega‑3 fatty acids, B‑vitamins (particularly B6, B12, and folate), vitamin D, iron, magnesium, and zinc have each been linked to impaired serotonin and dopamine pathways, heightened systemic inflammation, and dysregulation of the gut–brain axis, all of which contribute to depressive symptomatology. Because women experience higher rates of iron deficiency, greater hormonal fluctuation, and more frequent restrictive eating patterns, the impact of poor dietary quality is often amplified, underscoring the importance of nutritional assessment and intervention as part of comprehensive mental health care.127 Preventive dietary care is certainly recommended along with specialized oral hygiene instructions. Medications used to treat depression often create xerostomia; additional oral manifestations such as burning mouth syndrome and candidiasis can potentially develop, requiring detailed home care measures.128 Xerostomia can intensify gingival, periodontal and caries progression requiring specialized home care products tailored to address specific needs. Signs and symptoms consistent with depressive disorders typically display low motivation for self-care or total rejection of any health interest. Sensitive care and stress-free appointments are suggested when treating these individuals in order to respect their well-being and emotional status. Any abnormal behavior, distraught or angry feelings should be shared with their care provider immediately.