Considerations for Acquired and Inherited Blood Disorders

Course Number: 685

Clinical Characteristics and Implications for the Dental Provider

Figure 5: Characteristics and Special Considerations

Bleeding DisorderCharacteristics and Special Considerations
Mild hemophilia A
  • Prolonged bleeding may present after serious injury, trauma, or surgery, especially after dental surgery.
  • In many cases, mild hemophilia is not diagnosed until an injury, surgery or tooth extraction result in prolonged bleeding. The first episode may not occur until adulthood.
Moderate hemophilia A
  • Bruises easily
  • Prolonged bleeding may present after innocuous injuries.
  • May experience oral bleeding episodes
  • May have spontaneous bleeds into joints and muscles.
Severe hemophilia A
  • Likely experiences spontaneous bleeds into joints and muscles, including the TMJ.
  • Likely will experience oral bleeding at times
  • Spontaneous internal bleeding can occur
vWD
  • Bruises easily
  • Epistaxis
  • Menorrhagia
  • Oral bleeding possible
  • Mucocutaneous and operative bleeding
  • Bleeding with oropharyngeal surgery

Observing the clinical characteristics of the patient’s oral cavity along with developing a precise treatment plan, has significant implications for the patient. It is through these observations that the dentist must accurately convey the projected level of hemostatic challenge to the hematologist. Including specific details of the planned procedure is important, such as type of injection used (i.e. local submucosal infiltration, block anesthesia, involvement of bone vs soft tissues only, number of teeth extracted, staged procedures such as implant, etc. In turn, the hematologist will decide the appropriate factor coverage and treatment duration based on what has been observed and reported by the dentist.

Oral bleeding is extremely common with any genetic bleeding disorder, with up to 90% of individuals with hemophilia A experiencing oral bleeding at some point in their lives (Figure 6). As noted in Figure 6, oral cavity bleeding is a significant symptom of every bleeding disorder. Oral cavity bleeding is spontaneous and often reported by patients as a source of fear, frustration, and decreased quality of life.

Figure 6. Frequency of Oral Cavity Bleeding in Patients with Bleeding Disorders