Considerations for Acquired and Inherited Blood Disorders
Course Number: 685
Course Contents
Hemophilia A and Hemophilia B
Understanding the type and classification of the bleeding disorder is critical to the treatment planning process including anticipating potential treatment complications. Figure 3 demonstrates the two types of hemophilia, the severity level, and the percentage of the normal values of plasma level of factor associated with each bleeding disorder. In general, for men with hemophilia the bleeding tendency correlates with factor activity values. However, some patients may demonstrate more severe bleeding history than would be expected based on their factor level. This is especially important for women with hemophilia.
It is essential for the health and safety of the patient that all treatment plans include consultation with the patient’s hematologist/HTC. The hematologist/HTC will determine the hemostatic treatment plan specially tailored for the individual patient and the specific dental procedure that is needed and will share this with the dental provider and the patient.
Figure 3. Hemophilia A, and B: Types and Classifications of Severit
| Type | % Present within Total Bleeding Disorder* | Factor (F)Deficiency | % of Plasma Level of Factor |
|---|---|---|---|
| Mild hemophilia A | 33% | F VIII | 6-49% |
| Moderate hemophilia A | 16% | F VIII | 1-5% |
| Severe hemophilia A | 41% | FVIII | <1% |
| Mild hemophilia B | 31% | F IX | 6-49% |
| Moderate hemophilia B | 34% | F IX | 1-5% |
| Severe hemophilia B | 23% | FIX | <1% |
*Data reported by HTCs to CDC from 2012-2023. Missing percentages were the >40% factor level (assumed carriers) and individuals whose factor activity was marked "missing or unknown" in the report.